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Croscarmellose Sodium NF, Ph. Eur., JP

The superior disintegrant


Introducing Ac-Di-Sol® Croscarmellose Sodium, a highly regarded offering by IFF designed for pharmaceutical manufacturers. As an internally cross-linked sodium carboxymethyl cellulose (NaCMC), this product plays a crucial role in enhancing the disintegration and drug dissolution of various pharmaceutical forms like tablets, capsules, and granules.


Ac-Di-Sol® superdisintegrant excels at promoting rapid disintegration and drug dissolution with minimal usage in tablets, capsules, granules, and similar rapidly disintegrating dosage forms. Ac-Di-Sol® is renowned for its exceptional quality, consistency, and stability.


Ac-Di-Sol® SDW-802 Croscarmellose Sodium, a non-GMO superdisintegrant, is derived from wood pulp and represents a specialized grade of croscarmellose sodium. The choice of cellulose source significantly influences the effectiveness of a disintegrant by impacting its wicking and swelling properties. Through meticulous optimization of morphology and manufacturing processes, Ac-Di-Sol® SDW-802 delivers comparable disintegration performance to Ac-Di-Sol® SD-711 (which uses cotton-based material).


Key Features:
1. Superior Performance: Enables faster disintegration and dissolution compared to competitors, even at lower usage levels (1-2%), due to excellent water uptake and rapid swelling properties.
2. Broad Functionality: Compatible with various manufacturing processes such as direct compression, dry and wet granulation, and continuous manufacturing. It seamlessly supports different dosage forms, including tablets, capsules, and granules.
3. Purity: Boasts consistent critical material attributes, including fibrous morphology, low moisture content, minimal impurities, and low water-soluble content. These qualities ensure robust and dependable performance.


Choose Ac-Di-Sol® Croscarmellose Sodium for exceptional disintegration performance with enhanced reliability and versatility across pharmaceutical formulations.

  • Generic and alternative names

    Chemical Name: Cross-linked Sodium Carboxymethylcellulose

    Alternative names:

    • Croscarmellose sodium 
    • Ac-Di-Sol® SD-711 Croscarmellose Sodium
    • AcDiSol
    • Croscarmellose
    • Explocel
    • Kiccolate
    • Kiccolate ND 200


  • Claims / benefits / efficacy

    Product benefits

    • Super disintegrant
    • Superior quality
    • Superior performance at lower concentration
    • High-purity
    • Broad functionality
    • Improved cost performance
    • Non-GMO regulatory status
  • Function

    • Disintegrant
  • Application

    • Tablets
    • Oral Disintegrating Tablets

    Croscarmellose Sodiumis a super disintegrant used in pharmaceuticals in the synthesis of tablets for oral administration.

  • Grades

    Recommended Grades

    Differentiating Features

    Ac-Di-Sol® SD-711 croscarmellose sodium Premium grade for pharmaceutical and dietary supplement applications

    Ac-Di-Sol® SDW-802 croscarmellose sodium

    Non-GMO* regulatory status for pharmaceuticals and dietary supplements


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