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Avicel® PH (MCC)

Avicel® PH (MCC)

Microcrystalline Cellulose, NF, Ph. Eur., JP

Microcrystalline cellulose that enables easier processing, improved physical properties of tablets, and streamlined filling of capsules for more robust products. The introduction of Avicel PH was a catalyst for the pharmaceutical industry’s conversion to direct compression tablet technology, creating new levels of manufacturing efficiency. Today’s Avicel PH continues to set new standards, with enhanced grades designed to boost productivity and meet any formulation challenge.

  • Generic and alternative names

    • Avicel® PH Microcrystalline cellulose (MCC)
    • Chemical Name: 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose
  • Claims / benefits / efficacy

    • Improved powder flow
    • Optimum granule properties
    • Robust high shear wet granulation process
    • Improve tablet compression profile
    • Uniform tablet content
    • Increased batch size
    • Reduced moisture-related API degradation
  • Function

    • Filler
    • Diluent
  • Application

    • Direct compression tableting
    • Wet granulation
    • Extrusion and spheronization
    • Dry granulation roller compaction
  • Grades

    Available Grades Particle Size, μm Moisture, % Differentiating Features
    Avicel® PH-101 50 3.0 to 5.0 Wet Granulation
    Avicel® PH-102 100 3.0 to 5.0 Direct Compression
    Avicel® PH-105 20 NMT 5.0 Superior Compactability
    Avicel® PH-102 SCG 150 3.0 to 5.0 Superior Flow
    Avicel® PH-200 180 2.0 to 5.0 Superior Flow
    Avicel® PH-301 50 3.0 to 5.0 High Density
    Avicel® PH-302 100 3.0 to 5.0 High Density
    Avicel® PH-103 50 NMT 3 Low Moisture
    Avicel® PH-113 50 NMT 2 Low Moisture
    Avicel® PH-112 100 NMT 1.5 Low Moisture
    Avicel® PH-200 LM 180 NMT 1.5 Low Moisture
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