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Avicel® RC/CL

Avicel® RC/CL

Microcrystalline Cellulose and Sodium CMC NF, Ph. Eur.

 

Avicel RC / CL is a colloidal, water dispersible, spray-dried blend of microcrystalline cellulose and carboxymethylcellulose sodium.
Formulations which include this excipient have high thixotropy, low viscosity and display reduced settling.

Avicel® RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel® CL-611 is a stabilizer for reconstitutable or dry suspension formulations.

 

Dispersible cellulose grades, e.g. Avicel RC/CL grades (FMC Corp., USA), are commonly used in pharmaceutics, foods, and cosmetics as suspending aids to improve the stability and texture of other dispersive systems like emulsions, creams, lotions, etc.

  • Generic and alternative names

    • Avicel® Microcrystalline Cellulose Microcrystalline Cellulose Carboxymethylcellulose Sodium

    ALTERNATE PRODUCT NAME(S): Avicel® RC 501, 581, 591, CL 611

    Synonyms: Microcrystalline cellulose (INCI Name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethyl ether, Sodium CMC, Sodium salt, Cellulose gum

  • Claims / benefits / efficacy

    Product benefits

    • Improved powder flow

    • Superior compactibility and tablet compression profile

    • Enhanced mouth feel

    • Cost efficiency

    • Suspension rheology stabilizer

    • Avicel® RC: Ideal thixotropic behavior for stabilizing suspensions

    • Avicel® CL: Stabilizing reconstitutable or dry suspension formulations

  • Function

    • Suspending agent
    • Stabilizer
  • Application

    • Liquid
    • Suspension
    • Topical
  • Grades

    Product Co-Processed Components Particle Size Unique Benefit
    Avicel® RC Microcrystalline Cellulose Carboxymethylcellulose Sodium N/A Ideal thixotropic behavior for stabilizing suspensions

    Avicel® CL

    Microcrystalline Cellulose Carboxymethylcellulose Sodium N/A Stabilizing reconstitutable or dry suspension formulations

     

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