Avicel® RC/CL
Microcrystalline Cellulose and Sodium CMC NF, Ph. Eur.
Avicel RC / CL is a colloidal, water dispersible, spray-dried blend of microcrystalline cellulose and carboxymethylcellulose sodium.
Formulations which include this excipient have high thixotropy, low viscosity and display reduced settling.Avicel® RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel® CL-611 is a stabilizer for reconstitutable or dry suspension formulations.
Dispersible cellulose grades, e.g. Avicel RC/CL grades (FMC Corp., USA), are commonly used in pharmaceutics, foods, and cosmetics as suspending aids to improve the stability and texture of other dispersive systems like emulsions, creams, lotions, etc.
Generic and alternative names
- Avicel® Microcrystalline Cellulose Microcrystalline Cellulose Carboxymethylcellulose Sodium
ALTERNATE PRODUCT NAME(S): Avicel® RC 501, 581, 591, CL 611
Synonyms: Microcrystalline cellulose (INCI Name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethyl ether, Sodium CMC, Sodium salt, Cellulose gum
Claims / benefits / efficacy
Product benefits
-
Improved powder flow
-
Superior compactibility and tablet compression profile
-
Enhanced mouth feel
-
Cost efficiency
-
Suspension rheology stabilizer
-
Avicel® RC: Ideal thixotropic behavior for stabilizing suspensions
-
Avicel® CL: Stabilizing reconstitutable or dry suspension formulations
-
Function
- Suspending agent
- Stabilizer
Application
- Liquid
- Suspension
- Topical
Grades
Product Co-Processed Components Particle Size Unique Benefit Avicel® RC Microcrystalline Cellulose Carboxymethylcellulose Sodium N/A Ideal thixotropic behavior for stabilizing suspensions Avicel® CL
Microcrystalline Cellulose Carboxymethylcellulose Sodium N/A Stabilizing reconstitutable or dry suspension formulations