MEGGLE - high quality crystalline lactose producers, designed for DPIs MEGGLE has developed a specialty lactose grade, InhaLac®, to help meet the challenges associated with dry powder inhalation (DPI). Inhalation aerosols offers the potential for needle-free systemic delivery of small molecule drugs as well as therapeutic peptides and proteins. An industry standard in dry power inhalation formulation development, lactose monohydrate is used safely in DPI formulations. Using lactose as an excipient not only improves performance efficiency of the inhaler, but also facilitates powder handling during production. Effective performance of a dry powder inhaler largely depends on the carrier material used for the drug formulation. With our highly controlled production process different high quality sieved and milled grades are obtained, providing an adequate range of particle sizes – making them behave as individual particles. Particle size distribution [Laser diffraction] x10: 30-60 µm x50: 70-110 µm x90: 110-150 µm Typical Values Bulk Density [g/l]: 700 Tapped Density [g/l] : 850 Hausner factor: 1.21 Carrs index: 18 %
Generic and alternative namesLactose Monohydrate, Inhalation
Claims / benefits / efficacyDedicated production process Tailor-made products with specific powder characteristics Highest microbial quality including low endotoxins Available in a broad spectrum of sieve cuts to meet your criteria
ApplicationWith InhaLac®, MEGGLE can offer customized milled and sieved fractions - specifically and efficiently prepared to meet your DPI formulation needs.