Quatrefolic®
Quatrefolic® is a nutrient designed for all areas where folic acid and supplementation has been recommended and allowed. The terms folic acid and folate are often used interchangeably for the water-soluble B-complex vitamin, essential for the maintenance of cellular functions and health.
Quatrefolic® provides the active form of folate, 5-methyltetrahydrofolate (5-MTHF), naturally present in the body and available for its biological action. It has significant advantages over previous folate generations while maintaining the same biological properties of 5-methyltetrahydrofolate. Compared to standard folic acid, Quatrefolic® doesn’t lead to accumulation of Unmetabolized Folic Acid (UMFA) in the blood, which has no biological function and whose effects are not yet known.
Based on a critical evaluation of the available data, and on relevant biological and toxicological studies, an independent expert panel confirmed that Quatrefolic® is generally recognised as safe (GRAS) for use as a source of folate in conventional and medical foods.
Generic and alternative names
Generic name: Active Folate
Chemical name: glucosamine salt of (6S)-5-methyltetrahydrofolate
Claims / benefits / efficacy
• > 99% purity and GRAS status.
• Quatrefolic® passes the gastric barrier and is absorbed mainly in the small intestine by a carrier mediated mechanism. The carrier is not saturated and this ensures a higher folate uptake.
• In children it can improve energy production and the formation of red blood cells while promoting normal brain development and function. Moreover, the 5-MTHF can boost learning ability and memory.
• Can bypass folate metabolism disturbances, improving fertility, and increasing success rates in infertility treatment.
• May be particularly useful to provide the nutritionally active form of folate during preconceptions, pregnancy and lactation.
• May help postmenopausal women to normalize homocysteine, contributing to helping hot flashes, cardiovascular and bone health of aging women.
• Offers a homocysteine-lowering and -normalizing effect clinically proven.
• May help reduce unbalanced mood symptoms.
• May help with Glucose metabolism.
• Is a Gnosis by Lesaffre proprietary product with patents and trademark applications guaranteeing a wide range of use and covering all areas of folate application.
• Is produced according to cGMP, guaranteeing a reproducible quality profile.
• Vegetarian (does not come from animal sources)
Function
- Active ingredient
- Supplement
Application
- Can be used for combinations and formulations with vitamins and minerals, both for dietary supplements and Food & Beverage industry.
- Tablets, capsules, and soft gels
- Instant Drinks
- Unconventional dosage formulations such as granular and powdered microencapsulated forms delivered in sachets and powder blends.
Packaging
- 0,1 KG
- 0,5 KG
- 1 KG
- 5 KG
Certifications & Compliance
- Gluten-free
- Halal
- Kosher
- Lactose-free
- Non-GMO